Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

Hepatitis C virus (HCV) is hepatotropic and only infects humans and chimpanzees.Consequently, an immunocompetent small animal model is lacking.The restricted tropism of HCV likely reflects specific host factor requirements.We investigated if dominant restriction factors expressed in non-liver or non-human cell lines inhibit HCV propagation thus ren

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Modeling and Integrated Optimization of Power Split and Exhaust Thermal Management on Diesel Hybrid Electric Vehicles

To simultaneously achieve high fuel efficiency and low emissions in a diesel hybrid electric vehicle (DHEV), it is necessary to optimize not only power split but also exhaust thermal management for emission aftertreatment systems.However, how Sport Jug to coordinate the power split and the exhaust thermal management to balance fuel economy improvem

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